We discuss a case of fatal familial insomnia today, which presented with slight ataxia and subjective “shakiness”, then got transferred to the Psych department b/c of depression, delirium and insomnia, finally turned out to have inherited the disease from his father who died “at 55 from Alzheimer’s”; both his siblings were depressive and one was said to be an alcoholic, suffering from bouts of shakiness.
As references I can recommend
- a Lancet Neurology review from 2003
- a case report in the Nervenarzt from 2006
- a short review on Insomnia in Neurological Diseases from the Seminars in Neurology 2005