Differential diagnosis of adult leukencephalopathy

We face the following problem: a patient develops aphasia and apraxia suddenly – assumed ischemic. Her CT shows a diffuse leukencephalopathy which is more than your average SAE. What’s the differential?

There are also some new diseases on the horizon, of course acronymized. LTBL is one of them. 

How to differentiate MS from vascular lesions?

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