Despite the recent upheaval in the emergency medicine community about the ACEP tPA-for-stroke guidelines, thrombolysis is one of the two foundations of modern stroke medicine. In a local stroke symposium, I gave a talk about new developments and folklore in tpa-ology. It also exposes our Augsburg data on thrombolysis with bleeding rate and all you could wish in a real life tpa setting. The talk introduced a new acronym for remembering the various causes of tpa-related ICH (I love acronyms). It reads CORTEX
- C erebral amyloid angiopathy (extraischemic ICH)
- O ld stroke (old meaning > 6h)
- R ecanalization (recanalized vessels to dead tissue)
- T rauma (bleeding into contusions)
- E ndocarditis (rare but sometimes fatal)
- X – coagulation (think of factor X, anticoagulants, ASS and the like)
If you can read German, you might want to give the presentation a try – here is the prezi link.