Juvenile myoclonic epilepsy

Starting with a 19 yo patient with first ever generalized tonic clonic seizure in bed we discuss the management of first seizure, why it is necessary to perform an EEG early even if a possible trigger can be found and why idiopathic generalized epilepsy can still manifest first in more adult patients. It is actually quite hard to find good data about adults with generalized epilepsy, but some original research points out that quite a few of them can first manifest in higher ages – up to 75 years in small series.

Treatment is slowly changing, now that Levetiracetam is becoming a first line drug in idiopathic generalized epilepsy and there is also Zonisamide which proved efficacy in small series; otherwise valproate, lamotrigine and topiramate remain.

As for reviews, I found this, yet any good book on epilepsy does the job.


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